R&D Systems Inc. Tocris Bioscience Boston Biochem

RuBi-4AP

Cat. No. 3557

RuBi-4AP C30H28Cl2N8Ru [851956-02-0]

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Alternative Name: Rubi-4-aminopyridine

Chemical Name: bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex

Biological Activity

Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.

Licensing Information

Sold under licence from Columbia University

Technical Data

M.Wt:
672.58
Formula:
C30H28Cl2N8Ru
Solubility:
Soluble to 30 mM in water
Storage:
Store at -20°C
CAS No:
851956-02-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882. PMID: 12537482.

Nikolenko et al (2005) Two-photon uncaging of neurochemicals using inorganic metal complexes. Chem.Commun. 13 1752.

If you know of a relevant citation for this product please let us know.

Keywords: RuBi-4AP, supplier, voltage-dependent, gated, K+, potassium, channel, blockers, caged, 4-aminopyridine, hERG, Human, Ether-A-Go-Go, Gene, KCNQ

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