Tacrine hydrochloride

Cat. No. 0965

Tacrine hydrochloride C13H14N2.HCl [1684-40-8]

Price and Availability

For Tacrine hydrochloride pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride

Biological Activity

Potent cholinesterase inhibitor, a cognition enhancer in vivo.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
>99 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


Merck Index 12 9199.

Summers and Kaufman (1980) THA- A review of the literature and its use in treatment of five overdose patients. Clin.Toxicol. 16 269. PMID: 6994999.

Freeman and Dawson (1991) Tacrine: a pharmacological review. Prog.Neurobiol. 36 257. PMID: 1714613.

Osborne and Christie (1996) Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons. J.Pharmacol.Exp.Ther. 276 137. PMID: 8558423.

Snape et al (1999) A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology 38 181. PMID: 10193909.

If you know of a relevant citation for this product please let us know.

Keywords: Tacrine hydrochloride, supplier, Cholinesterase, inhibitor, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Research Product Guide

Updated in 2015, this guide highlights over 275 products for neurodegeneration research. Request a copy or view PDF today.

divider line

Alzheimer's Disease: Neurobiology and Drug Targets

Written by Alan Palmer

Alzheimer's Poster

Updated in 2015, this poster summarises the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.

divider line

New Product Guide


Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.