Cat. No. 0965
Chemical Name: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride
Biological ActivityPotent cholinesterase inhibitor, a cognition enhancer in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Merck Index 12 9199.
Summers and Kaufman (1980) THA- A review of the literature and its use in treatment of five overdose patients. Clin.Toxicol. 16 269. PMID: 6994999.
Freeman and Dawson (1991) Tacrine: a pharmacological review. Prog.Neurobiol. 36 257. PMID: 1714613.
Osborne and Christie (1996) Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons. J.Pharmacol.Exp.Ther. 276 137. PMID: 8558423.
Snape et al (1999) A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology 38 181. PMID: 10193909.
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Keywords: Tacrine hydrochloride, supplier, Cholinesterase, inhibitor, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic
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