Cat. No. 0965
Chemical Name: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride
Biological ActivityPotent cholinesterase inhibitor, a cognition enhancer in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Merck Index 12 9199.
Summers and Kaufman (1980) THA- A review of the literature and its use in treatment of five overdose patients. Clin.Toxicol. 16 269. PMID: 6994999.
Freeman and Dawson (1991) Tacrine: a pharmacological review. Prog.Neurobiol. 36 257. PMID: 1714613.
Osborne and Christie (1996) Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons. J.Pharmacol.Exp.Ther. 276 137. PMID: 8558423.
Snape et al (1999) A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology 38 181. PMID: 10193909.
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Keywords: Tacrine hydrochloride, supplier, Cholinesterase, inhibitor, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic