Cat. No. 3505
Chemical Name: 4-[[(2,3-Dihydro-1,1,3,3-tetramethy
Biological ActivityRARα-selective agonist (Ki = 2 nM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Taneja et al (1996) Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 93 6197.
Dilworth et al (1999) Ligand-dependent activation of transcription in vitro by retinoid acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo. Proc.Natl.Acad.Sci.USA 96 1995.
Gehin et al (1999) Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem.Biol. 6 519. PMID: 10421757.
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Keywords: BMS 753, supplier, retinoic, acid, agonists, rara, raralpha, rar-α, selective, BMS753
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