Cat. No. 3505
Chemical Name: 4-[[(2,3-Dihydro-1,1,3,3-tetramethy
Biological ActivityRARα-selective agonist (Ki = 2 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Taneja et al (1996) Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 93 6197.
Dilworth et al (1999) Ligand-dependent activation of transcription in vitro by retinoid acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo. Proc.Natl.Acad.Sci.USA 96 1995.
Gehin et al (1999) Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem.Biol. 6 519. PMID: 10421757.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: BMS 753, supplier, retinoic, acid, agonists, rara, raralpha, rar-α, selective, BMS753
Find multiple products by catalog number
New Products in this Area
Selective estrogen receptor modulator (SERM)Rifaximin
Pregnane X receptor agonist; antibioticS 07662
Inverse agonist of the constitutive androstane receptor (CAR)
March 28 - April 1, 2015