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(±)-CP 47497

Cat No. 3500

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Chemical Name: rel-5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohex yl]phenol

Biological Activity

Potent CB₁ receptor agonist (K_i = 2.2 nM). Display 3-28-fold > potency than Δ⁹-THC. Exhibits analgesic, motor depressant, anticonvulsant and hypothermic effects in vivo.

Technical Data

M.Wt:

318.49

Formula:

C₁₂H₃₄O₂

Solubility:

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Purity:

>98 %

Storage:

Store at -20°C

CAS No:

[70434-82-1]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

Material Safety Data Sheet: View current batch

References

Weissman et al (1982) Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol. J.Pharmacol.Exp.Ther. 223 516. Melvin et al (1993) Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol.Pharmacol. 44 1008. Huffman et al (2008) Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg.Med.Chem. 16 322.

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Keywords: (±)-CP 47497, Potent, CB1, agonists, cannabinoids, Receptors, (±)-CP47497, cb1r

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