4-IPP

Cat No. 3429new product

4-IPP C10H7IN2 [41270-96-6]

Price and Availability

For 4-IPP pricing & availability please select your country from the drop down menu:
Submit

Chemical Name: 4-Iodo-6-phenylpyrimidine

Biological Activity

Inhibitor of macrophage migration inhibitor factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo. Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro.

Technical Data

M.Wt:
282.08
Formula:
C10H7IN2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
[41270-96-6]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Winner et al (2008) A novel, macrophage migration inhibitor factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res. 68 7253.

If you know of a useful citation for this product please let us know.

View Related Products by Target

Keywords: 4-IPP, macrophage, migration, inhibitor, factor, (MIF), inhibitors, suicide, substrates, cytokines, cytokine

Buy Now / Print Quote

Find multiple products by catalog number


divider line

Print Quote Facility

Order via your purchasing department

Print Quote Facility

It's now even easier to place orders via your purchasing department.

Simply add a product to your cart & click on the "Print Quote" button.

more
divider line

Modulators of Peripheral Sensitization

Written by M.R. Vasko and G.D. Nicol

Pain Poster

'Pharmacological Modulators of Peripheral Sensitization' summarizes the inhibitory and excitatory modulators of peripheral sensitization.

request
divider line

Signal Transduction Guide

Signal Transduction Guide

A collection of more than 600 products for signal transduction research. View PDF today.

request
divider line

Cancer Research Guide

Cancer Research Guide

Highlights over 400 products for cancer research. Request a copy or view PDF today.

request
divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

request
divider line

Immunology Guide

Immunology Research Guide

Highlights over 150 products for immunology research. Request a copy or view PDF today.

request
divider line

New Products in this Area

SD 1008

JAK2/STAT3 signaling pathway inhibitor

4-IPP

Inhibitor of macrophage migration inhibitor factor (MIF); suicide substrate

Cardamonin

Inhibitor of NF-κB activation; anti-inflammatory

Sign-up for new product e-alerts
divider line

Careers at Tocris

Careers at Tocris

Tocris Bioscience currently has opportunities for a Chemistry Technician.

If you would like to be considered for any positions not currently advertised, we welcome your speculative application.

submit