Cat. No. 3429
Chemical Name: 4-Iodo-6-phenylpyrimidine
Biological ActivityInhibitor of macrophage migration inhibitory factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo. Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Winner et al (2008) A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res. 68 7253. PMID: 18794110.
If you know of a relevant citation for this product please let us know.
Keywords: 4-IPP, supplier, macrophage, migration, inhibitory, factors, MIF, inhibitors, suicide, substrates, cytokines, 4IPP
Find multiple products by catalog number
New Products in this Area
mSTING agonist; induces antitumor immunological responsesC 87
TNF-α inhibitorJTE 607 dihydrochloride
Cytokine release inhibitor; anti-inflammatoryCRID3 sodium salt
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
November 5-9, 2015