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4-IPPCat No.
3429
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Price and Availability |
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Chemical Name: 4-Iodo-6-phenylpyrimidine |
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Biological Activity
Inhibitor of macrophage migration inhibitor factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo. Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro.Technical Data
M.Wt:282.08
Formula:C10H7IN2
Solubility:Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity: >99 %
Storage:Store at +4°C
CAS No:[41270-96-6]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Winner et al (2008) A novel, macrophage migration inhibitor factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res. 68 7253.If you know of a useful citation for this product please let us know.
Keywords: 4-IPP, macrophage, migration, inhibitor, factor, (MIF), inhibitors, suicide, substrates, cytokines, cytokine
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