Cat. No. 3429

4-IPP C10H7IN2 [41270-96-6]

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Chemical Name: 4-Iodo-6-phenylpyrimidine

Biological Activity

Inhibitor of macrophage migration inhibitory factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo. Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
>99 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Winner et al (2008) A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res. 68 7253. PMID: 18794110.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: 4-IPP, supplier, macrophage, migration, inhibitory, factors, MIF, inhibitors, suicide, substrates, cytokines, 4IPP

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