R&D Systems Inc. Tocris Bioscience Boston Biochem

RuBi-GABA

Cat. No. 3400

RuBi-GABA C42H39F6N5O2P2Ru [1028141-88-9]

Price and Availability

For RuBi-GABA pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (bis(2,2'-Bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex

Biological Activity

Ruthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.

Licensing Information

Sold under licence from Columbia University

Technical Data

M.Wt:
922.8
Formula:
C42H39F6N5O2P2Ru
Solubility:
Soluble to 10 mM in water
Storage:
Store at -20°C
CAS No:
1028141-88-9

Resources

Other Information

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882. PMID: 12537482.

Rial Verde et al (2008) Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits 2 2. PMID: 18946542.

If you know of a relevant citation for this product please let us know.

Keywords: RuBi-GABA, supplier, Caged, GABA, GABAA, GABAC, Receptors, GABAB

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

GABA Review

GABA Receptors Review

Written by Ian Martin, Norman Bowery & Susan Dunn. Request a copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development.

divider line

New Product Guide

NPG

Highlights 150 new products added in the second half of 2014. View PDF today.

divider line

New Products in this Area

Elinogrel

P2Y12 inhibitor

Ractopamine hydrochloride

Trace amine 1 (TA1) receptor agonist

TG 4-155

High affinity and selective EP2 receptor antagonist

SAG

Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway

DC 260126

FFA1 (GPR40) antagonist

AR-C 118925XX

Selective, competitive P2Y2 receptor antagonist

EPPTB

Trace amine 1 (TA1) receptor antagonist/inverse agonist

NIBR 189

Potent and selective EBI2 (GPR183) receptor antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

AACR 2015

AACR 2015

April 18 - 22, 2015

Philadelphia, PA

Booth: 2135