Cat. No. 3400
Chemical Name: (bis(2,2'-Bipyridine-N,N')triphenylph
Biological ActivityRuthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.
Licensing InformationSold under licence from Columbia University
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882. PMID: 12537482.
Rial Verde et al (2008) Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits 2 2. PMID: 18946542.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: RuBi-GABA, supplier, Caged, GABA, GABAA, GABAC, Receptors, GABAB
Find multiple products by catalog number
New Products in this Area
Potent and selective smoothened (Smo) receptor antagonistGSK 137647
Potent and selective FFA4 (GPR120) agonistAH 7614
Selective FFA4 (GPR120) antagonistProsaptide TX14(A)
Potent GPR37 and GPR37L1 agonistAS 2034178
Selective FFA1 (GPR40) agonist(±)-NBI 74330
Potent and selective CXCR3 antagonistPurmorphamine
Smo receptor agonistCTCE 9908
CXCR4 antagonist; antitumorVUF 11207 fumarate
Potent CXCR7 agonistTC-G 1006
Potent and selective sphingosine-1-phosphate receptor 1 (S1P1) agonist
September 8 - 9, 2014