R&D Systems Inc. Tocris Bioscience Boston Biochem

BHQ

Cat. No. 1236

BHQ C14H22O2 [88-58-4]

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Chemical Name: 1,4-Dihydroxy-2,5-di-tert-butylbenzene

Biological Activity

A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.

Technical Data

M.Wt:
222.33
Formula:
C14H22O2
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
88-58-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Hassessian et al (1994) Blockade of the inward rectifier potassium current by the Ca2+-ATPase inhibitor 2',5'-di(tert-butyl)-1,4-benzohydroquinone (BHQ). Br.J.Pharmacol. 112 1118. PMID: 7952872.

Dettbarn and Palade (1999) Effects of three sarcoplasmic/endoplasmic Ca++ pump inhibitors on release channels and intracellular stores. J.Pharmacol.Exp.Ther. 285 739. PMID: 9580621.

Fusi et al (1999) 2,5-Di-t-butyl-1,4 benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta. Eur.J.Pharmacol. 366 181. PMID: 10082199.

Jan et al (1999) Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced Ca2+ signals in Madin Darby canine kidney cells. Eur.J.Pharmacol. 365 111. PMID: 9988129.

If you know of a relevant citation for this product please let us know.

Keywords: BHQ, supplier, Inhibitors, SERCA, ATPase, Ca2+, modulators, Ca2+-ATPase, Signaling, Signalling, Calcium, P-Type, ATPases, Calcium-ATPase, Ion, Transporters, Pumps

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