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CART (62-76) (rat, human)

Cat No. 3339

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Alternative Name: Cocaine and amphetamine-regulated transcript (62-76)(rat, human)

Biological Activity

Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.

Technical Data

M.Wt:

1570.77

C₆₄H₉₉N₁₇O₂₃S₃

YGQVPMCDAGEQCAV

Store at -20°C

[210978-19-1]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

Material Safety Data Sheet: View current batch

References

Volkoff and Peter (2000) Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain Res. 887 125. Vaarmann and Kask (2001) Cocaine and amphetamine-regulated transcript peptide (CART_62-76)-induced changes in regional monoamine levels in rat brain. Neuropeptides 35 292. Colombo et al (2003) Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on release of insulin from isolated rat islets. Pancreas 27 161.

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Keywords: CART (62-76) (rat, human), Neuromodulating, neuropeptide, fragment, inhibits, inhibitors, food, intake, vivo, Peptide, Receptor, Receptors, Cocaine-, and, amphetamine-regulated, transcript, CART, peptide, , amphetamine

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