VU 1545

Cat No. 3325

VU 1545 C22H15FN4O3 [890764-63-3]

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Chemical Name: N-[1-(2-Fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-4-nitro benzamide

Biological Activity

Metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).

Technical Data

M.Wt:
402.38
Formula:
C22H15FN4O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
[890764-63-3]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

de Paulis et al (2006) Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. J.Med.Chem. 49 3332.

If you know of a useful citation for this product please let us know.

Keywords: VU 1545, mGlu5, mGluR5, positive, allosteric, modulators, mGlur, Group, I, Receptors, Glutamate, Metabotropic, VU1545

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