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Home »
Pharmacology » 7-TM Receptors » Glutamate (Metabotropic) Receptors » Glutamate (Metabotropic) Group I Receptors » VU 1545
VU 1545Cat No. 3325 |
Price and Availability |
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Chemical Name: N-[1-(2-Fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-4-nitro benzamide |
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Biological Activity
Metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).Technical Data
M.Wt:402.38
Formula:C22H15FN4O3
Solubility:Soluble to 100 mM in DMSO
Purity: >98 %
Storage:Store at +4°C
CAS No:[890764-63-3]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
de Paulis et al (2006) Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. J.Med.Chem. 49 3332.If you know of a useful citation for this product please let us know.
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Keywords: VU 1545, mGlu5, mGluR5, positive, allosteric, modulators, mGlur, Group, I, Receptors, Glutamate, Metabotropic, VU1545
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