Prochlorperazine dimaleate

Cat. No. 3287

Prochlorperazine dimaleate C20H24ClN3S.2C4H4O4 [84-02-6]

Price and Availability

For Prochlorperazine dimaleate pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-Chloro-10-[3[(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine dimaleate

Biological Activity

D2 receptor antagonist. Also interacts with 5-HT3 and nAChR. Displays antipsychotic, antispasmodic, antiemetic and antinociceptive activity in vivo.

Technical Data

M.Wt:
606.09
Formula:
C20H24ClN3S.2C4H4O4
Solubility:
Soluble to 25 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
84-02-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Lummis and Baker (1997) Radioligand binding and photoaffinity labeling studies show a direct interaction of phenothiazenes at 5-HT3 receptors. Neuropharmacology 36 665. PMID: 9225292.

Ghelardini et al (2004) Prochlorperazine induces central antinociception mediated by the muscarinic system. Pharmacol.Res. 50 351. PMID: 15225680.

Satoh et al (2005) The antipsychotic and antiemetic drug prochlorperazine delays the ventricular repolarization of the in situ canine heart. J.Pharm.Sci. 97 101.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Prochlorperazine dimaleate, supplier, D2, receptor, antagonists, 5-HT3, nAChR, Dopamine, Receptors, serotonin, dopaminergic

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Research Guide

Highlights over 250 products for neurodegeneration research. Request a copy or view PDF today.

divider line

Dopamine Review

Dopamine Review

Written by Phillip G. Strange and revised by Kim Neve. Request a copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Poster

Updated in 2014 - this poster summarizes the neurobiology of Parkinson's disease (PD), including new genetic insight, neurotransmitter pathways, and the role of aberrant α-synuclein metabolism in PD pathogenesis.

divider line

New Product Guide

NPG

Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

New Products in this Area

Aripiprazole

High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

IBRO 2015

IBRO 2015

July 7 - 11, 2015

Rio de Janeiro, Brazil

Booth: B21