Pentamidine isethionateCat No. 3277 |
Price and Availability |
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Chemical Name: 4,4'-(Pentamethylenedioxy)dibenzamidine bis-2-hydroxyethanesulfonate salt |
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Biological Activity
Antimicrobial. Neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a NMDA glutamate receptor antagonist.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Reynolds and Aizeman (1992) Pentamidine is an N-methyl-D-aspartate receptor antagonist and is neuroprotective in vitro. J. Neurosci. 12 970. Kitamura et al (1995) Inhibition of constitutive nitric oxide synthase in the brain by pentamidine, a calmodulin antagonist. Eur.J.Pharmacol. 289 299.If you know of a useful citation for this product please let us know.
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Keywords: Pentamidine isethionate, Antimicrobial, inhibits, inhibitors, constitutive, nNOS, NMDA, antagonist, receptors, Nitric, Oxide, Signaling, Signalling, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Neuronal, Nitric, oxide, Synthases
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