Cat. No. 3258
Alternative Name: Ametycine
Chemical Name: [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(ami
Biological ActivityAntibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Tomasz et al (1987) Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235 1204. PMID: 3103215.
Bizanek et al (1992) Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry 31 3084. PMID: 1554696.
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Keywords: Mitomycin C, supplier, inhibitors, DNA, synthesis, cross-linking, antitumor, agents, Apoptosis, Inducer, MitomycinC, antibiotics