R&D Systems Inc. Tocris Bioscience Boston Biochem

Mitomycin C

Cat. No. 3258

Mitomycin C C15H18N4O5 [50-07-7]

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Alternative Name: Ametycine

Chemical Name: [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione

Biological Activity

Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis.

Technical Data

M.Wt:
334.33
Formula:
C15H18N4O5
Solubility:
Soluble to 5 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
50-07-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Tomasz et al (1987) Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235 1204. PMID: 3103215.

Bizanek et al (1992) Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry 31 3084. PMID: 1554696.

If you know of a relevant citation for this product please let us know.

Keywords: Mitomycin C, supplier, inhibitors, DNA, synthesis, cross-linking, antitumor, agents, Apoptosis, Inducer, MitomycinC, antibiotics

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