WWL 70

Cat. No. 3252

WWL 70 C27H23N3O3 [947669-91-2]

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Chemical Name: N-Methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl carbamic acid ester

Biological Activity

Potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM), an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol (Cat. No. 1298).

Technical Data

M.Wt:
437.49
Formula:
C27H23N3O3
Solubility:
Soluble to 10 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
947669-91-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Blankman et al (2007) A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonylglycerol. Chem.Biol. 14 1347. PMID: 18096503.

Li et al (2007) A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases. J.Am.Chem.Soc. 129 9594. PMID: 17629278.

If you know of a relevant citation for this product please let us know.

Keywords: WWL 70, supplier, WWL70, potent, ABHD6, inhibitors, αβ-hydrolase, domain, 6, alphabeta-hydrolase, endocannabinoids, 2-arachidonylglycerol, hydrolysis, inhibits

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