TCS PrP Inhibitor 13Cat No. 3238 |
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Chemical Name: 2,4-Dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
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Biological Activity
Antiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM).Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Kimata et al (2007) New series of antiprion compounds: pyrazolone derivatives have potent activity of inhibiting protease-resistant prion protein accumulation. J.Med.Chem. 50 5053.If you know of a useful citation for this product please let us know.
Keywords: TCS PrP Inhibitor 13, Antiprion, agent, potently, inhibits, inhibitors, PrP-res, accumulation, Prion, Protein, Neuronal, Metabolism, TCSPrP, Inhibitor13
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