Cat. No. 3231
Biological ActivityN-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation.
(Modifications: Gln-1 = N-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Walther et al (2000) A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Mol.Cell 5 831. PMID: 10882119.
Karlsson et al (2005) Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors. J.Leuko.Biol. 78 762.
Rabiert et al (2007) The N-formyl peptide receptors and the anaphylatoxin C5a receptors: an overview. Biochimie 89 1089. PMID: 17428601.
If you know of a relevant citation for this product please let us know.
Keywords: Ac9-25, supplier, Annexin, I, N-terminal, peptide, Acts, FPR1, ligands, FPRL, Formyl, Peptide, Receptors
Find multiple products by catalog number
New Products in this Area
Selective motilin receptor antagonistAdipoRon hydrochloride
Orally active AdipoR1 and AdipoR2 agonist; antidiabeticPG 931
Potent and selective MC4 receptor agonistCYM 50769
Novel non-peptide NPBWR1 antagonist
Win $1,000 Product Credit
April 26 - 30, 2014
San Diego CA, USA
Booth Number: 918