CP 376395 hydrochlorideCat No. 3212 |
Price and Availability |
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Chemical Name: N-(1-Ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenox y)-4-pyridinamine hydrochloride |
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Biological Activity
Potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Chen et al (2008) 2-Aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J.Med.Chem. 51 1385.If you know of a useful citation for this product please let us know.
Keywords: CP 376395 hydrochloride, Potent, selective, CRF1, antagonists, Corticotropin-Releasing, Factor1, Receptors, CP376395, hydrochloride
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