R&D Systems Inc. Tocris Bioscience Boston Biochem

Doxercalciferol

Cat. No. 3206

Doxercalciferol C28H44O2 [54573-75-0]

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Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-7α-methyl-1-[(1R,2E)-1,4,5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

Biological Activity

Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

Technical Data

M.Wt:
412.65
Formula:
C28H44O2
Solubility:
Soluble to 50 mM in ethanol and to 10 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
54573-75-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Brown et al (2006) The vitamin D prodrugs 1α(OH)D2, 1α(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyriod cells. Nephrol.Dial.Transplant. 21 644. PMID: 16221703.

Noonan et al (2008) Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol.Dial.Transplant. 23 3824. PMID: 18644798.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Doxercalciferol, supplier, Vitamin, D2, VDR, agonists, D, Receptors, VDR-like

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