Doxercalciferol

Cat. No. 3206

Doxercalciferol C28H44O2 [54573-75-0]

Price and Availability

For Doxercalciferol pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-7α-methyl-1-[(1R,2E)-1,4,5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

Biological Activity

Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

Technical Data

M.Wt:
412.65
Formula:
C28H44O2
Solubility:
Soluble to 50 mM in ethanol and to 10 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
54573-75-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Brown et al (2006) The vitamin D prodrugs 1α(OH)D2, 1α(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyriod cells. Nephrol.Dial.Transplant. 21 644. PMID: 16221703.

Noonan et al (2008) Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol.Dial.Transplant. 23 3824. PMID: 18644798.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Doxercalciferol, supplier, Vitamin, D2, VDR, agonists, D, Receptors, VDR-like

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

divider line

Nuclear Receptors Product Listing

Nuclear Receptors Product Listing

Highlights over 150 products for nuclear receptors. Request copy or view PDF today.

divider line

New Product Guide

NPG

Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

New Products in this Area

FICZ

High affinity aryl hydrogen receptor (AhR) agonist

ML 179

Selective liver receptor homolog 1 (LRH1) inverse agonist

AC 186

Potent and selective ERβ agonist; neuroprotective

Isotretinoin

Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation

BTC

Selective estrogen receptor modulator (SERM)

Sign-up for new product e-alerts
divider line

Bio-Techne Events

FEBS 2015

40th FEBS Congress: The Biochemical Basis of Life

July 4 - 9, 2015

Berlin, Germany