KM 11060

Cat. No. 3143

KM 11060 C19H17Cl2N3O2S [774549-97-2]

Price and Availability

For KM 11060 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in ethanol
>98 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Robert et al (2008) Structural analog of Sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol.Pharmacol. 73 478. PMID: 17975008.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: KM 11060, supplier, Corrects, F508del-CFTR, trafficking, Cl-, Channels, VSAC, Chloride, KM11060, pharmacochaperones

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris


Enter your email address below to sign up to receive our email updates:

divider line

New Products in this Area

PA 1 dihydrochloride

Photoswitchable ENaC blocker

GlyH 101

Reversible, voltage-dependent CFTR chloride channel blocker

QAQ dichloride

Photoswitchable Nav, Kv and Cav channel blocker

AAQ chloride

Photoswitchable Kv channel blocker


Mitochondria VDAC modulator; also Ferroptosis activator

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Pharmacology 2015

Pharmacology 2015

December 15 - 17, 2015

London UK