Cat. No. 3130

Cannabinol C21H26O2 [521-35-7]

Price and Availability

For Cannabinol pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: CBN

Chemical Name: 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol

Biological Activity

CB2 and CB1 receptor agonist (Ki values are 126 and 211 nM respectively). Inhibits adenylyl cyclase (EC50 values are 120 and 261 nM for CB1 and CB2 receptors respectively) and suppresses immune cell function. Major constituent of cannabis; displays little or no psychotropic activity.

Technical Data

Soluble to 50 mM in DMSO and to 10 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Rhee et al (1997) Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylyl cyclase. J.Med.Chem. 40 3228. PMID: 9379442.

Herring et al (1998) Inhibition of the cyclic AMP signaling cascade and nuclear factor binding to CRE and kB elements by cannabinol, a minimally CNS-active cannabinoid. Biochem.Pharmacol. 55 1013. PMID: 9605425.

Zygmunt et al (2002) Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism. J.Neurosci. 22 4720. PMID: 12040079.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Cannabinol, supplier, cannabinoids, CB1, CB2, receptors, agonists, not, psychoactive

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Research Product Guide

Updated in 2015, this guide highlights over 275 products for neurodegeneration research. Request a copy or view PDF today.

divider line

Cannabinoid Review

Cannabinoid Receptor Ligands Review

Written by Roger Pertwee, an expert. Request a copy or view PDF today.

divider line

New Product Guide


Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

New Products in this Area

AM 6545

High affinity and selective CB1 antagonist

ML 193

Potent, selective GPR55 antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Pharmacology 2015

Pharmacology 2015

December 15 - 17, 2015

London UK