1-Deoxymannojirimycin hydrochloride

Cat. No. 1259

1-Deoxymannojirimycin hydrochloride C6H13NO4.HCl [73465-43-7]

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Chemical Name: (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride

Biological Activity

Selective inhibitor of α-mannosidase I.

Technical Data

Soluble to 50 mM in water
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Bischoff and Kornfeld (1984) The effect of 1-deoxymannojirimycin on rat liver α-mannosidases. Biochem.Biophys.Res.Commun. 125 324. PMID: 6239623.

Fuhrmann et al (1984) Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides. Nature 307 755. PMID: 6230538.

Bischoff et al (1986) The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells. J.Biol.Chem. 261 4766. PMID: 2937779.

If you know of a relevant citation for this product please let us know.

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Keywords: 1-Deoxymannojirimycin hydrochloride, supplier, α-mannosidase, alpha-mannosidase, I, inhibitors, a-Mannosidase, Glycosylases, Carbohydrate, Metabolism, antibiotics, Glycosylase Inhibitors

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