3-Bromo-7-nitroindazole

Cat. No. 0735

3-Bromo-7-nitroindazole
 C7H4BrN3O2 [74209-34-0]

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Biological Activity

Potent inhibitor of rat cerebellar nitric oxide synthase; more potent than 7-nitroindazole (Cat. No. 0602).

Technical Data

M.Wt:
242.03
Formula:
C7H4BrN3O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
>98 %
Storage:
Desiccate at +4°C
CAS No:
74209-34-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Bland-Ward et al (1994) Isoform selectivity of indazole-based nitric oxide synthase inhibitors. Br.J.Pharmacol. 112 351P.

Bland-Ward and Moore (1995) 7-Nitroindazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci. 57 PL131. PMID: 7544863.

If you know of a relevant citation for this product please let us know.

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Keywords: 3-Bromo-7-nitroindazole, supplier, Selective, nNOS, inhibitors, Nitric, Oxide, Signaling, Signalling, Neuronal, NO, Synthases, Tocris Bioscience, nNOS Inhibitors

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