Cat. No. 3090
Chemical Name: 3',4',5',6'-Tetrahydroxyspiro[isobenzof
Biological ActivityInhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Lehmann et al (2008) Small molecule disruption of G protein βγ subunit signaling inhibits neutrophil chemotaxis and inflammation. Mol.Pharmacol. 73 410. PMID: 18006643.
Ukhanov et al (2011) Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons. J.Neurosci. 31 273. PMID: 21209212.
If you know of a relevant citation for this product please let us know.
Keywords: Gallein, supplier, inhibitors, betagamma, signaling, G, Proteins, Heterotrimeric
Find multiple products by catalog number
New Products in this Area
Potent C5a receptor peptide antagonistRU-SKI 43 hydrochloride
Hedgehog acyltransferase (Hhat) inhibitor; cell permeableFLI 06
Inhibitor of Notch signalingCASIN
Cdc42 GTPase inhibitor
September 8 - 9, 2014