HU 308Cat No. 3088 |
Price and Availability |
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Chemical Name: 4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dime thylbicyclo[3.1.1]hept-2-ene-2-methanol |
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Biological Activity
Potent and selective CB2 receptor agonist (Ki values are 22.7 nM and > 10 μM for CB2 and CB1 receptors respectively, EC50 = 5.57 nM). Displays antiallodynic activity in the rat hindpaw incision model of postoperative pain.Licensing Information
Sold under license from Hebrew University of Jerusalem.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Hanus et al (1999) HU-308: a specific agonist for CB2, a peripheral cannabinoid receptor. Proc.Natl.Acad.Sci.USA 96 14228. LaBuda et al (2005) Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. Eur.J.Pharmacol. 527 172. Garcia-Arencibia et al (2007) Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: Importance of antioxidant and cannabinoid receptor-independent properties. Brain Res. 1134 162.If you know of a useful citation for this product please let us know.
Keywords: HU 308, Potent, selective, CB2, agonists, cannabinoids, Receptors, HU308, cb2r
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