R&D Systems Inc. Tocris Bioscience Boston Biochem

Nocodazole

Cat. No. 1228

Nocodazole C14H11N3O3S [31430-18-9]

Price and Availability

For Nocodazole pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester

Biological Activity

Microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion.

Technical Data

M.Wt:
301.32
Formula:
C14H11N3O3S
Solubility:
Soluble to 50 mM in DMSO
Purity:
>95 %
Storage:
Store at RT
CAS No:
31430-18-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Vasquez et al (1997) Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol.Biol.Cell 8 973. PMID: 9201709.

Mikhailov and Gundersen` (1998) Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxol. Cell.Motil.Cytoskeleton 41 325. PMID: 9858157.

Webb et al (2004) Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases. Int.J.Biochem.Cell Biol. 36 2541. PMID: 15325591.

Mizushima et al (2010) Methods in mammalian autophagy research. Cell 140 313. PMID: 20144757.

If you know of a relevant citation for this product please let us know.

Keywords: Nocodazole, supplier, Microtubule, inhibitors, Tau, Tubulin, Microtubules, Mitosis

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Research Guide

Highlights over 250 products for neurodegeneration research. Request a copy or view PDF today.

divider line

New Product Guide

NPG

Highlights 150 new products added in the second half of 2014. View PDF today.

divider line

New Products in this Area

Dimethylenastron

Inhibitor of mitotic motor kinesin Eg5

MPC 6827 hydrochloride

Inhibitor of microtubule polymerization; antimitotic and antitumor

SB 743921 hydrochloride

Potent kinesin spindle protein (KSP) inhibitor

Sign-up for new product e-alerts
divider line

Bio-Techne Events

DPG 2015

BNA 2015: Festival of Neuroscience

April 12 - 15, 2015

Edinburgh, UK

Booth: 33