BRL 37344, sodium salt
Cat. No. 0948
Chemical Name: (R*,R*)-(±)-4-[2-[(2-(3-Chlorophenyl
Biological ActivityPotent and selective β3 adrenoceptor agonist (Ki values are 287, 1750 and 1120 nM for β3, β1 and β2 receptors respectively). Also available as part of the β-Adrenoceptor Agonist Tocriset™.
Licensing InformationSold with the permission of GlaxoSmithKline
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Arch et al (1984) Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature 309 163. PMID: 6325935.
Ayo Oriowo et al (1996) The selectivity in vitro of the sterioisomers of the beta-3 adrenoreceptor agonist BRL 37344. J.Pharmacol.Exp.Ther. 277 22. PMID: 8613923.
Strosberg and Pietri-Rouxel (1996) Function and regulation of the β3-adrenoceptor. TiPS 17 373. PMID: 8979772.
Board et al (2000) BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro. Eur.J.Pharmacol. 406 33. PMID: 11011029.
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Keywords: BRL 37344, sodium salt, supplier, β3-adrenoceptor, b3-adrenoceptor, agonists, β3-adrenergic, b3-adrenergic, Receptors, BRL37344, sodium, salt, GlaxoSmithKline, GSK
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