R&D Systems Inc. Tocris Bioscience Boston Biochem

Bifemelane hydrochloride

Cat. No. 0767

Bifemelane hydrochloride C18H23NO.HCl [62232-46-6]

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Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride

Biological Activity

Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

Technical Data

M.Wt:
305.84
Formula:
C18H23NO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
62232-46-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Tobe et al (1981) Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 31 1278. PMID: 7197535.

Naoi et al (1988) 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 50 243. PMID: 3335842.

Nomoto et al (1994) Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 178 95. PMID: 7816348.

If you know of a relevant citation for this product please let us know.

Keywords: Bifemelane hydrochloride, supplier, MAO-A, MAO-B, inhibitors, Monoamine, oxygenases, Oxidases

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