R&D Systems Inc. Tocris Bioscience Boston Biochem

Bifemelane hydrochloride

Cat. No. 0767

Bifemelane hydrochloride C18H23NO.HCl [62232-46-6]

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Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride

Biological Activity

Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

Technical Data

M.Wt:
305.84
Formula:
C18H23NO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
62232-46-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Tobe et al (1981) Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 31 1278. PMID: 7197535.

Naoi et al (1988) 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 50 243. PMID: 3335842.

Nomoto et al (1994) Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 178 95. PMID: 7816348.

If you know of a relevant citation for this product please let us know.

Keywords: Bifemelane hydrochloride, supplier, MAO-A, MAO-B, inhibitors, Monoamine, oxygenases, Oxidases

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