Cat. No. 0131
Chemical Name: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofur
Biological ActivityMethochloride salt of (+)-bicuculline (Cat. No. 0130). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Kemp et al (1986) Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation. Br.J.Pharmacol. 87 677. PMID: 3011168.
Seutin et al (1997) Evidence for a non-GABAergic action of quaternary salts of bicuculline on dopaminergic neurones. Neuropharmacology 36 1653. PMID: 9517436.
Seutin and Johnson (1999) Recent advances in the pharmacology of quaternary salts of bicuculline. TiPS 20 268. PMID: 10390643.
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Keywords: (-)-Bicuculline methochloride, supplier, Water-soluble, GABAA, antagonists, Receptors
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