Cat. No. 0130
Chemical Name: [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one
Biological ActivityClassical GABAA antagonist. Methoiodide salt (Cat. No. 2503), Methobromide salt (Cat. No. 0109) and Methochloride salt (Cat. No. 0131) also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Merck Index 12 1250.
Curtis et al (1970) GABA, bicuculline and central inhibition. Nature 226 1222. PMID: 4393081.
Olsen et al (1976) Studies on the neuropharmacological activity of bicuculline and related compounds. Brain Res. 102 283. PMID: 1247886.
Piredda et al (1985) Intracerebral site of convulsant action of bicuculline. Life Sci. 36 1295. PMID: 3982215.
Sieghart et al (1989) Multiplicity of GABAA-benzodiazepine receptors. TiPS 10 407. PMID: 2559519.
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Keywords: (+)-Bicuculline, supplier, Potent, GABAA, antagonists, Receptors
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