R&D Systems Inc. Tocris Bioscience Boston Biochem

BD 1047 dihydrobromide

Cat. No. 0956

BD 1047 dihydrobromide C13H20Cl2N2.2HBr [138356-21-5]

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Chemical Name: N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide

Biological Activity

σ1 receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ1 and σ2 sites.

Technical Data

M.Wt:
437.04
Formula:
C13H20Cl2N2.2HBr
Solubility:
Soluble to 50 mM in water and to 50 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
138356-21-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Matsumoto et al (1995) Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol. 280 301. PMID: 8566098.

Garrone et al (2000) Effects of trazodone on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol. 400 35. PMID: 10913582.

Romieu et al (2000) Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 11 2885. PMID: 11006959.

If you know of a relevant citation for this product please let us know.

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Keywords: BD 1047 dihydrobromide, supplier, σ1, sigma1, selective, antagonist, receptors, BD1047, dihydrobromide

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