R&D Systems Inc. Tocris Bioscience Boston Biochem

BD 1047 dihydrobromide

Cat. No. 0956

BD 1047 dihydrobromide C13H20Cl2N2.2HBr [138356-21-5]

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Chemical Name: N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide

Biological Activity

σ1 receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ1 and σ2 sites.

Technical Data

M.Wt:
437.04
Formula:
C13H20Cl2N2.2HBr
Solubility:
Soluble to 50 mM in water and to 50 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
138356-21-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Matsumoto et al (1995) Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol. 280 301. PMID: 8566098.

Garrone et al (2000) Effects of trazodone on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol. 400 35. PMID: 10913582.

Romieu et al (2000) Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 11 2885. PMID: 11006959.

If you know of a relevant citation for this product please let us know.

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Keywords: BD 1047 dihydrobromide, supplier, σ1, sigma1, selective, antagonist, receptors, BD1047, dihydrobromide

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