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(RS)-Baclofen

Cat. No. 0417

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Chemical Name: (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid

Biological Activity

Selective GABA_B receptor agonist. Skeletal muscle relaxant. (R)-Baclofen (Cat. No. 0796) also available.

Technical Data

M.Wt:

213.66

Formula:

C₁₀H₁₂CINO₂

Solubility:

Soluble to 100 mM in 1eq. NaOH

Purity:

>99 %

Storage:

Store at RT

CAS No:

1134-47-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Other Information

R-enantiomer Available

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Hill et al (1981) ³H-Baclofen and ³H-GABA bind to bicuculline-insensitive GABA_B sites in rat brain. Nature 290 149. PMID: 6259535.

Berthelot et al (1991) 3-Thienylaminobutyric acid and 3-furylaminobutyric acids - synthesis and GABA_B receptor binding studies. J.Med.Chem. 34 2557. PMID: 1652022.

Bowery et al (1993) GABA_B receptor pharmacology. Annu.Rev.Pharmacol.Toxicol. 33 109. PMID: 8388192.

If you know of a relevant citation for this product please let us know.

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