Cat. No. 0416
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-
Biological ActivityA Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Deana et al (1984) Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem.J. 218 899. PMID: 6721841.
Berger et al (1991) Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS-035. Naunyn Schmiedebergs Arch.Pharmacol. 344 653. PMID: 1775198.
If you know of a relevant citation for this product please let us know.
Keywords: YS-035 hydrochloride, supplier, inhibitors, K+, outward, pacemaker, current, Potassium, Channels, Non-Selective
Find multiple products by catalog number
New Products in this Area
Potent KCa3.1 blockerBDS I
Potent and reversible Kv3.4 potassium channel blocker; neuroprotectiveAgitoxin 2
Potent Shaker K+ channel blockerMaxiPost
Potassium channel modulator; exerts subtype-specific effectsML 277
Selective Kv7.1 (KCNQ1) potassium channel activator; augments IKs current
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.