Cat. No. 1085
Biological ActivityPeptide neurotoxin; selectively and reversibly blocks N-type calcium channels.
(Modifications: X = Hyp, Disulfide bridge between 1 - 16, 8 - 19, 15 - 26, Tyr-27 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Tsien et al (1988) Multiple types of neuronal calcium channels and their selective modulation. TiNS 11 431. PMID: 2469160.
Casali et al (1997) Different effects of reducing agents on ω-conotoxin GVIA inhibition of [3H]-acetylcholine release from rat cortical slices and guinea-pig myenteric plexus. Br.J.Pharmacol. 120 88. PMID: 9117104.
Wright and Angu (1997) Prolonged cardiovascular effects of the N-type Ca2+ channel antagonist ω-conotoxin GVIA in conscious rabbits. J.Cardiovasc.Pharmacol. 30 392. PMID: 9300325.
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Keywords: w-Conotoxin GVIA, supplier, Ca2+, channel, blockers, N-type, Calcium, CaV, Channels, voltage-gated, voltage-dependent, omega-Conotoxin, ω-conotoxin, GVIA, neurotoxins
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