Signal Transduction
Stem Cells
Signaling Pathways
Product Type
All Products
New Products
Small Molecules
Peptides
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
BW-B 70CCat. No. 1304 |
Price and AvailabilityBy clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy. |
|
Chemical Name: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea |
Biological Activity
Potent, selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailability in vivo.Certificate of Analysis / Safety Data Sheet
References
Salmon et al (1990) Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents. Adv.Prost.Throm.Leuk.Res. 21 109. PMID: 1847758.
Payne et al (1991) Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma. Agents Actions Suppl. 34 189. PMID: 1793063.
Yeadon et al (1993) Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs. Agents Actions 38 8. PMID: 8480540.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: BW-B 70C, supplier, 5-lipoxygenase, inhibitors, oxygenases, inhibits, oxidases, BWB70C, 5-LOX
Quick Order
Find multiple products by catalog number
Immunology Guide
Highlights over 150 products for immunology research. Request a copy or view PDF today.
New Products in this Area
Cyclooxygenase-inhibiting nitric oxide donor
20% Discount*
Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.