Tyrphostin B44, (-) enantiomer
Cat. No. 0578
Chemical Name: (R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide
Biological ActivityPotent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer (Cat. No. 0579). Selective over ErbB2.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896. PMID: 1676428.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: (-)-Tyrphostin B44, supplier, EGFR, kinase, inhibitors, Epidermal, Growth, Factor, Receptors, ErbB, Her, RTK, Receptor, Tyrosine, Kinases, RTKs, (-)-TyrphostinB44
Find multiple products by catalog number
Win a Kindle
June 23 - 26, 2013