Ouabain

Cat. No. 1076

Ouabain C29H44O12 [630-60-4]

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Chemical Name: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11α,14,19-pentahydoxycard-20(22)-enolide

Biological Activity

Selective Na+, K+-ATPase inhibitor.

Technical Data

M.Wt:
584.66
Formula:
C29H44O12
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
>95 %
Storage:
Desiccate at -20°C
CAS No:
630-60-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 7031.

Croyle et al (1997) Extensive random mutagenesis analysis of the Na/K+ ATPase alpha subunit identifies known and previously unidentified amino acid residues that alter ouabain sensitivity-implications for ouabain binding. Eur.J.Biochem. 248 488. PMID: 9346307.

Hosoi et al (1997) Isoform-specific up-regulation by ouabain of Na+, K+-ATPase in cultured rat astrocytes. J.Neurochem. 69 2189. PMID: 9349566.

Marjorie et al (1997) Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn Schmiedebergs Arch.Pharmacol. 356 203. PMID: 9272726.

If you know of a relevant citation for this product please let us know.

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Keywords: Ouabain, supplier, Na+K+-ATPases, inhibitors, Ion, Pumps, Transporters

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