R&D Systems Inc. Tocris Bioscience Boston Biochem

Ouabain

Cat. No. 1076

Ouabain C29H44O12 [630-60-4]

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Chemical Name: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11α,14,19-pentahydoxycard-20(22)-enolide

Biological Activity

Selective Na+, K+-ATPase inhibitor.

Technical Data

M.Wt:
584.66
Formula:
C29H44O12
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
>95 %
Storage:
Desiccate at -20°C
CAS No:
630-60-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 7031.

Croyle et al (1997) Extensive random mutagenesis analysis of the Na/K+ ATPase alpha subunit identifies known and previously unidentified amino acid residues that alter ouabain sensitivity-implications for ouabain binding. Eur.J.Biochem. 248 488. PMID: 9346307.

Hosoi et al (1997) Isoform-specific up-regulation by ouabain of Na+, K+-ATPase in cultured rat astrocytes. J.Neurochem. 69 2189. PMID: 9349566.

Marjorie et al (1997) Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn Schmiedebergs Arch.Pharmacol. 356 203. PMID: 9272726.

If you know of a relevant citation for this product please let us know.

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Keywords: Ouabain, supplier, Na+K+-ATPases, inhibitors, Ion, Pumps, Transporters

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