Sulprostone

Cat. No. 3049

Sulprostone C23H31NO7S [60325-46-4]

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Chemical Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide

Biological Activity

Selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.

Technical Data

M.Wt:
465.56
Formula:
C23H31NO7S
Solubility:
Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)
Storage:
Store at -20°C
CAS No:
60325-46-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Narumiya et al (1999) Prostanoid receptors: Structures, properties, and functions. Phys.Rev. 79 1193.

Gil et al (2008) Transient allodynia pain models in mice for assessment of analgesic activity. Br.J.Pharmacol. 153 769. PMID: 17700719.

If you know of a relevant citation for this product please let us know.

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Keywords: Sulprostone, supplier, Sulprostone, prostaglandin, prostanoid, EP1, EP3, receptor, agonist, Tocris Bioscience, Prostanoid Receptor Agonists

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