SKF 38393 hydrobromide

Cat. No. 0922

SKF 38393 hydrobromide C16H17NO2.HBr [20012-10-6]

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Chemical Name: (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide

Biological Activity

Prototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).

Technical Data

Soluble to 25 mM in water with gentle warming and to 25 mM in ethanol with gentle warming
>99 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Sibley et al (1982) Interactions of novel dopaminergic ligands with D1 and D2 dopamine receptors. Life Sci. 31 637. PMID: 6127585.

Seeman and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15 264. PMID: 7940991.

Geter-Douglass et al (1997) Characterization of unconditioned behavioral effects of dopamine D3/D2 receptor agonists. J.Pharmacol.Exp.Ther. 283 7. PMID: 9336302.

Habuchi et al (1997) Dopamine stimulation of cardiac β-adrenoceptors: the involvement of sympathetic amine transporters and the effect of SKF38393. Br.J.Pharmacol. 122 1669. PMID: 9422813.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: SKF 38393 hydrobromide, supplier, Selective, D1-like, agonists, Dopamine, D1, Receptors, D5, dopaminergic, SKF38393, hydrobromide

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