R&D Systems Inc. Tocris Bioscience Boston Biochem

SKF 38393 hydrobromide

Cat. No. 0922

SKF 38393 hydrobromide C16H17NO2.HBr [20012-10-6]

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Chemical Name: (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide

Biological Activity

Prototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).

Technical Data

M.Wt:
336.23
Formula:
C16H17NO2.HBr
Solubility:
Soluble to 25 mM in water with gentle warming and to 25 mM in ethanol with gentle warming
Purity:
>99 %
Storage:
Desiccate at -20°C
CAS No:
20012-10-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Sibley et al (1982) Interactions of novel dopaminergic ligands with D1 and D2 dopamine receptors. Life Sci. 31 637. PMID: 6127585.

Seeman and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15 264. PMID: 7940991.

Geter-Douglass et al (1997) Characterization of unconditioned behavioral effects of dopamine D3/D2 receptor agonists. J.Pharmacol.Exp.Ther. 283 7. PMID: 9336302.

Habuchi et al (1997) Dopamine stimulation of cardiac β-adrenoceptors: the involvement of sympathetic amine transporters and the effect of SKF38393. Br.J.Pharmacol. 122 1669. PMID: 9422813.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: SKF 38393 hydrobromide, supplier, Selective, D1-like, agonists, Dopamine, D1, Receptors, D5, dopaminergic, SKF38393, hydrobromide

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