SKF 38393 hydrobromide
Cat. No. 0922
Chemical Name: (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)
Biological ActivityPrototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Sibley et al (1982) Interactions of novel dopaminergic ligands with D1 and D2 dopamine receptors. Life Sci. 31 637. PMID: 6127585.
Seeman and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15 264. PMID: 7940991.
Geter-Douglass et al (1997) Characterization of unconditioned behavioral effects of dopamine D3/D2 receptor agonists. J.Pharmacol.Exp.Ther. 283 7. PMID: 9336302.
Habuchi et al (1997) Dopamine stimulation of cardiac β-adrenoceptors: the involvement of sympathetic amine transporters and the effect of SKF38393. Br.J.Pharmacol. 122 1669. PMID: 9422813.
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Keywords: SKF 38393 hydrobromide, supplier, Selective, D1-like, agonists, Dopamine, D1, Receptors, D5, dopaminergic, SKF38393, hydrobromide
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High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
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