R&D Systems Inc. Tocris Bioscience Boston Biochem

RU 24969 hemisuccinate

Cat. No. 0912

RU 24969 hemisuccinate C14H16N2O.C4H6O4 [66611-27-6]

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Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Biological Activity

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data

M.Wt:
287.34
Formula:
C14H16N2O.½C4H6O4
Solubility:
Soluble to 50 mM in DMSO and to 30 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
66611-27-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties. Eur.J.Med.Chem. 22 33.

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412. PMID: 8450834.

Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129. PMID: 10837852.

If you know of a relevant citation for this product please let us know.

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Keywords: RU 24969 hemisuccinate, supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2OC4H6O4

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