RU 24969 hemisuccinate

Cat. No. 0912

RU 24969 hemisuccinate C14H16N2O.C4H6O4 [66611-27-6]

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Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Biological Activity

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data

Soluble to 50 mM in DMSO and to 30 mM in water
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties. Eur.J.Med.Chem. 22 33.

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412. PMID: 8450834.

Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129. PMID: 10837852.

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Keywords: RU 24969 hemisuccinate, supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2O.0.5C4H6O4

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