R&D Systems Inc. Tocris Bioscience Boston Biochem

RU 24969 hemisuccinate

Cat. No. 0912

RU 24969 hemisuccinate C14H16N2O.C4H6O4 [66611-27-6]

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Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Biological Activity

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data

M.Wt:
287.34
Formula:
C14H16N2O.½C4H6O4
Solubility:
Soluble to 50 mM in DMSO and to 30 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
66611-27-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties. Eur.J.Med.Chem. 22 33.

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412. PMID: 8450834.

Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129. PMID: 10837852.

If you know of a relevant citation for this product please let us know.

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Keywords: RU 24969 hemisuccinate, supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2OC4H6O4

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