Cat. No. 1069
Alternative Name: TTx citrate
Chemical Name: Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol citrate
Biological ActivityHighly selective, reversible sodium channel blocker; citrate salt of tetrodotoxin.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Merck Index 12 9382.
Kao (1972) Pharmacology of tetrodotoxin and saxitoxin. Fed.Proc. 31 1117. PMID: 5032475.
Kao (1986) Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann.N.Y.Acad.Sci. 479 52. PMID: 2434008.
Gleitz et al (1996) The protective action of tetrodotoxin and (±)-kavain on anaerobic glycolysis, ATP content and intracellular Na+ and Ca2+ of anoxic brain vesicles. Neuropharmacology 35 1743. PMID: 9076753.
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Keywords: Tetrodotoxin citrate, supplier, Citrate, salt, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Na+