R&D Systems Inc. Tocris Bioscience Boston Biochem

Tetrodotoxin citrate

Cat. No. 1069

Tetrodotoxin citrate C11H17N3O8 [18660-81-6]

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Alternative Name: TTx citrate

Chemical Name: Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol citrate

Biological Activity

Highly selective, reversible sodium channel blocker; citrate salt of tetrodotoxin.

Technical Data

M.Wt:
319.27
Formula:
C11H17N3O8
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at -20°C
CAS No:
18660-81-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 9382.

Kao (1972) Pharmacology of tetrodotoxin and saxitoxin. Fed.Proc. 31 1117. PMID: 5032475.

Kao (1986) Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann.N.Y.Acad.Sci. 479 52. PMID: 2434008.

Gleitz et al (1996) The protective action of tetrodotoxin and (±)-kavain on anaerobic glycolysis, ATP content and intracellular Na+ and Ca2+ of anoxic brain vesicles. Neuropharmacology 35 1743. PMID: 9076753.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Tetrodotoxin citrate, supplier, Citrate, salt, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Na+

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