Cat. No. 1200
Chemical Name: N5-[Imino(propylamino)methyl]-L-orn
Biological ActivityHighly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.
Licensing InformationSold under license.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869. PMID: 9397167.
Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91. PMID: 11404282.
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Keywords: Nw-Propyl-L-arginine hydrochloride, supplier, selective, inhibitor, nNOS, Nitric, Oxide, Signaling, Signalling, Neuronal, NO, Synthases, Nomega-Propyl-L-arginine, hydrochloride, Tocris Bioscience, nNOS Inhibitors