R&D Systems Inc. Tocris Bioscience Boston Biochem

Nω-Propyl-L-arginine hydrochloride

Cat. No. 1200

Nw-Propyl-L-arginine hydrochloride C9H20N4O2.HCl [137361-05-8]

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Chemical Name: N5-[Imino(propylamino)methyl]-L-ornithine hydrochloride

Biological Activity

Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.

Licensing Information

Sold under license.

Technical Data

M.Wt:
252.74
Formula:
C9H20N4O2.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
137361-05-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869. PMID: 9397167.

Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91. PMID: 11404282.

If you know of a relevant citation for this product please let us know.

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Keywords: Nw-Propyl-L-arginine hydrochloride, supplier, selective, inhibitor, nNOS, Nitric, Oxide, Signaling, Signalling, Neuronal, NO, Synthases, Nomega-Propyl-L-arginine, hydrochloride

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