Nω-Propyl-L-arginine hydrochloride

Cat. No. 1200

Nw-Propyl-L-arginine hydrochloride C9H20N4O2.HCl [137361-05-8]

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Chemical Name: N5-[Imino(propylamino)methyl]-L-ornithine hydrochloride

Biological Activity

Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.

Licensing Information

Sold under license.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869. PMID: 9397167.

Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91. PMID: 11404282.

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Keywords: Nw-Propyl-L-arginine hydrochloride, supplier, selective, inhibitor, nNOS, Nitric, Oxide, Signaling, Signalling, Neuronal, NO, Synthases, Nomega-Propyl-L-arginine, hydrochloride, nNOS Inhibitors

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