R&D Systems Inc. Tocris Bioscience Boston Biochem

Nitrendipine

Cat. No. 0601

Nitrendipine C18H20N2O6 [39562-70-4]

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Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitro­phenyl)-3,5-pyridine dicarboxylic acid ethyl methyl ester

Biological Activity

L-type calcium channel blocker.

Technical Data

M.Wt:
360.37
Formula:
C18H20N2O6
Solubility:
Soluble to 50 mM in DMSO and to 25 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
39562-70-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 6667.

Watanabe et al (1995) L-type calcium channel block by highly hydrophilic dihydropyridines in single ventricular cells of guinea-pig hearts. J.Mol.Cell.Cardiol. 27 1271. PMID: 8531209.

Costa et al (1996) Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain. Neurochem.Res. 21 537. PMID: 8726959.

Fleming et al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9. PMID: 21164513.

If you know of a relevant citation for this product please let us know.

Keywords: Nitrendipine, supplier, Ca2+, channel, blockers, L-type, Calcium, CaV, Channels, voltage-gated, voltage-dependent

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