Cat. No. 1190
Biological ActivityIrreversible inhibitor of aspartic proteases. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with E 64d (Cat. No. 4545).
(Modifications: Val-1 = N-terminal H-iso-Valeryl, Val-2 = Val-4-amino-3-hydroxy-6-methyl
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Merck Index 12 7290.
Marciniszyn et al (1976) Mode of inhibition of acid proteases by pepstatin. J.Biol.Chem. 251 7088. PMID: 993206.
Sato et al (2007) Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res. 67 9677. PMID: 17942897.
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Keywords: Pepstatin A, supplier, Aspartic, protease, inhibitors, Proteases, Proteinases, PepstatinA
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July 23 - 27, 2014
Bonn University, Germany