R&D Systems Inc. Tocris Bioscience Boston Biochem

Muscimol

Cat. No. 0289

Muscimol C4H6N2O2 [2763-96-4]

Price and Availability

For Muscimol pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 5-Aminomethyl-3-hydroxyisoxazole

Biological Activity

Potent GABAA receptor agonist and partial GABAC receptor agonist. Inhibits memory retention and attenuates airway constriction in vivo.

Technical Data

M.Wt:
114.1
Formula:
C4H6N2O2
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Store at RT
CAS No:
2763-96-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488. PMID: 5752907.

Akhondzadeh and Stone (1995) Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors. Br.J.Pharmacol. 115 527. PMID: 7582468.

Johnstone (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319. PMID: 8885697.

Gleason et al (2009) The GABAA agonist muscimol attenuates induced airway constriction in guinea pigs in vivo. J.Appl.Physiol. 106 1257. PMID: 19213928.

Jafari-Sabet and Jannat-Dastjerdi (2009) Muscimol state-dependent memory: involvement of dorsal hippocampal μ-opioid receptors. Behav.Brain Res. 202 5. PMID: 19447274.

If you know of a relevant citation for this product please let us know.

Keywords: Muscimol, supplier, Potent, GABAA, agonists, Partial, GABAC, Receptors

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

GABA Review

GABA Receptors Review

Written by Ian Martin, Norman Bowery & Susan Dunn. Request a copy or view PDF today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Poster

A summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request a copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development.

divider line

New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

divider line

Bio-Techne Events

Human Proteome Organisation World Congress 2014

Human Proteome Organisation World Congress 2014

October 5 - 8, 2014

Madrid, Spain