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MTPGCat. No. 0855 |
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Chemical Name: (RS)-α-Methyl-4-tetrazolylphenylglycine |
Biological Activity
Group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
References
Jane et al (1995) New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 34 851. PMID: 8532166.
Bedingfield et al (1996) Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. Eur.J.Pharmacol. 309 71. PMID: 8864696.
Bushell et al (1996) Pharmacological antagonism of the actions of group II and group III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br.J.Pharmacol. 117 1457. PMID: 8730739.
If you know of a relevant citation for this product please let us know.
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Keywords: MTPG, supplier, Group, II, group, III, mGlur, antagonists, selective, Receptors, mGlu2, mGlu3, mGluR3, mGluR2, Glutamate, Metabotropic
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