Cat. No. 0854
Chemical Name: (RS)-α-Methyl-4-sulfonophenylglycine
Biological ActivityRelatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Jane et al (1995) New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 34 851. PMID: 8532166.
Thomas et al (1995) Antagonism of L-AP4- and (1S,3S)-ACPD-induced depression of dorsal root-evoked monosynaptic excitation of neonatal rat motoneurones by the novel antagonists MSPG and MPPG. Br.J.Pharmacol. 114 9P.
Bedingfield et al (1996) Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. Eur.J.Pharmacol. 309 71. PMID: 8864696.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: MSPG, supplier, Group, III, group, II, mGlur, antagonists, Receptors, mGlu4, mGlu6, mGlu7, mGlu8, mGluR4, mGluR6, mGluR7, mGluR8, Glutamate, Metabotropic, mGlu2, mGlu3, mGluR2, mGluR3
Find multiple products by catalog number
New Products in this Area
Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonistAZ 12216052
Positive allosteric modulator at mGlu8LSN 2463359
Potent and selective positive allosteric modulator at mGlu5XAP 044
Potent and selective mGlu7 antagonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.