R&D Systems Inc. Tocris Bioscience Boston Biochem

MSPG

Cat. No. 0854

MSPG C9H11NO5S [169209-64-7]

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Chemical Name: (RS)-α-Methyl-4-sulfonophenylglycine

Biological Activity

Relatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors.

Technical Data

M.Wt:
245.25
Formula:
C9H11NO5S
Solubility:
Soluble to 100 mM in 1eq. NaOH
Storage:
Store at RT
CAS No:
169209-64-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Jane et al (1995) New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 34 851. PMID: 8532166.

Thomas et al (1995) Antagonism of L-AP4- and (1S,3S)-ACPD-induced depression of dorsal root-evoked monosynaptic excitation of neonatal rat motoneurones by the novel antagonists MSPG and MPPG. Br.J.Pharmacol. 114 9P.

Bedingfield et al (1996) Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. Eur.J.Pharmacol. 309 71. PMID: 8864696.

If you know of a relevant citation for this product please let us know.

Keywords: MSPG, supplier, Group, III, group, II, mGlur, antagonists, Receptors, mGlu4, mGlu6, mGlu7, mGlu8, mGluR4, mGluR6, mGluR7, mGluR8, Glutamate, Metabotropic, mGlu2, mGlu3, mGluR2, mGluR3

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