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MK 212 hydrochloride

Cat. No. 0941

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Chemical Name: 6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride

Biological Activity

5-HT_2C serotonin receptor agonist.

Technical Data

M.Wt:

235.12

Formula:

C₈H₁₁CIN₄.HCl

Solubility:

Soluble to 50 mM in water with gentle warming

Purity:

>99 %

Storage:

Store at RT

CAS No:

64022-27-1

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

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Safety Data Sheet: View Safety Data Sheet

References

Conn and Sanders-Bush (1987) Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT₂ and 5-HT_1C) receptors. J.Pharmacol.Exp.Ther. 242 552. PMID: 3039120.

Lee et al (1992) Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol.Psychiatry 31 460. PMID: 1581424.

Hemrick-Luecke and Fuller (1996) Involvement of 5-HT_2A receptors in the elevation of rat serum corticosterone concentration by quipazine and MK-212. Eur.J.Pharmacol. 311 207. PMID: 8891601.

If you know of a relevant citation for this product please let us know.

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