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Minoxidil

Cat. No. 0583

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Chemical Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide

Biological Activity

Antihypertensive. Antialopecia agent. K_ir6 channel (K_ATP) activator.

Technical Data

M.Wt:

209.25

Formula:

C₉H₁₅N₅O

Solubility:

Soluble to 25 mM in ethanol and to 25 mM in DMSO with gentle warming

Purity:

>99 %

Storage:

Store at RT

CAS No:

38304-91-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 6290.

Meisheri et al (1993) Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 45 271. PMID: 8435087.

Tsoporis et al (1993) Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 11 1337. PMID: 8133016.

Lachgar et al (1998) Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 138 407. PMID: 9580790.

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