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Benazepril hydrochloride

Cat. No. 2578

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Alternative Name: CGS 14824A

Chemical Name: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

Biological Activity

Non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

Technical Data

M.Wt:

460.96

Formula:

C₂₄H₂₈N₂O₅.HCl

Solubility:

Soluble to 50 mM in water and to 100 mM in DMSO

Purity:

>99 %

Storage:

Desiccate at +4°C

CAS No:

86541-74-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Ishibashi et al (1991) Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs. Cardiovas.Drugs Ther. 5 635.

Takemori et al (1991) Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneous hypertensive rats. Arzneim.-Forsch. 41 612.

Yamamoto et al (1991) General pharmacology of the novel angiotensin converting enzyme inhibitor benazepril hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics. Arzneim.-Forsch. 41 913.

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