R&D Systems Inc. Tocris Bioscience Boston Biochem

Benazepril hydrochloride

Cat. No. 2578

Benazepril hydrochloride C24H28N2O5.HCl [86541-74-4]

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Alternative Name: CGS 14824A

Chemical Name: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

Biological Activity

Non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

Technical Data

M.Wt:
460.96
Formula:
C24H28N2O5.HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
86541-74-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Ishibashi et al (1991) Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs. Cardiovas.Drugs Ther. 5 635.

Takemori et al (1991) Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneous hypertensive rats. Arzneim.-Forsch. 41 612.

Yamamoto et al (1991) General pharmacology of the novel angiotensin converting enzyme inhibitor benazepril hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics. Arzneim.-Forsch. 41 913.

If you know of a relevant citation for this product please let us know.

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Keywords: Benazepril hydrochloride, supplier, Angiotensin-converting, enzyme, ACE, inhibitors, Proteinases, Proteases, CGS14824A

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