Cat. No. 2568
Biological ActivityMyelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. Induces strong T and B cell responses and is highly encephalitogenic.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Ichikawa et al (1996) Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55. J.Immunol. 157 919. PMID: 8752946.
Slavin et al (1998) Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28 109. PMID: 9771980.
Zhang et al (2004) T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6xSJL) F1 mice. J.Neuroimmunol. 148 1. PMID: 14975581.
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Keywords: MOG (35-55), supplier, Encephalitogenic, myelin, oligodendrocyte, glycoprotein, fragment, Neuronal, Metabolism