R&D Systems Inc. Tocris Bioscience Boston Biochem

PLP (139-151)

Cat. No. 2567

PLP (139-151) His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe

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Alternative Name: Proteolipid protein (139-151)

Biological Activity

Synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.

Technical Data

M.Wt:
1521.74
Formula:
C72H104N20O17
Sequence:
HSLGKWLGHPDKF
Solubility:
Soluble to 1 mg/ml in 20% acetonitrile / water
Storage:
Desiccate at -20°C
CAS No:
122018-58-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Tuohy et al (1989) Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J.Immunol. 142 1523. PMID: 2465343.

Sobel et al (1990) Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J.Neuropathol.Exp.Neurol. 49 468. PMID: 2273404.

Kuchroo et al (1991) Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology. 59 305. PMID: 1716908.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: PLP (139-151), supplier, Encephalitogenic, myelin, proteolipid, fragment, Neuronal, Metabolism

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