Cat. No. 2567
Alternative Name: Proteolipid protein (139-151)
Biological ActivitySynthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Tuohy et al (1989) Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J.Immunol. 142 1523. PMID: 2465343.
Sobel et al (1990) Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J.Neuropathol.Exp.Neurol. 49 468. PMID: 2273404.
Kuchroo et al (1991) Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology. 59 305. PMID: 1716908.
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Keywords: PLP (139-151), supplier, Encephalitogenic, myelin, proteolipid, fragment, Neuronal, Metabolism